Effects of Microplastic Exposure on Human Digestive, Reproductive, and Respiratory Health: A Rapid Systematic Review
Reports Andrew Craigie Reports Andrew Craigie

Effects of Microplastic Exposure on Human Digestive, Reproductive, and Respiratory Health: A Rapid Systematic Review

We concluded that exposure to microplastics is “unclassifiable” for birth outcomes and gestational age in humans on the basis of the “low” and “very low” quality of the evidence. We concluded that microplastics are “suspected” to harm human reproductive, digestive, and respiratory health, with a suggested link to colon and lung cancer. Future research on microplastics should investigate additional health outcomes impacted by microplastic exposure and identify strategies to reduce exposure.

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Buildings’ Hidden Plastic Problem
Reports Andrew Craigie Reports Andrew Craigie

Buildings’ Hidden Plastic Problem

In this brief, we present highlights from the significant body of science indicating that plastic building materials are contributing to serious health and environmental harms over their life cycle, from fossil fuel extraction to production, use, and disposal. These impacts fall disproportionately on susceptible and marginalized people, including women, children, Indigenous people, low-income communities, and people of color. We share examples of solutions and offer recommendations to strengthen policies that will reduce plastic use in the built environment and associated life cycle harms.

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Presence of microplastics in human stomachs
Reports Andrew Craigie Reports Andrew Craigie

Presence of microplastics in human stomachs

This study presents the first definitive confirmation of microplastic presence in the human stomach, based on samples from 26 cadavers. 97 microplastic particles were extracted from stomach contents, across all 26 individuals, revealing a universal prevalence of microplastics in the cadavers.

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Association of mixed exposure to microplastics with sperm dysfunction: a multi-site study in China
Reports Andrew Craigie Reports Andrew Craigie

Association of mixed exposure to microplastics with sperm dysfunction: a multi-site study in China

Our findings highlight the potential reproductive health risks posed by microplastic contamination, particularly PTFE, a non-stick pan coating material, and raise concerns about the potential of urine testing as an indicator of male reproductive microplastic exposure. Future research is warranted to further elucidate the mechanisms underlying the adverse effects of microplastics on male fertility and cross-generational effects.

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Microplastics in the Olfactory Bulb of the Human Brain
Reports Andrew Craigie Reports Andrew Craigie

Microplastics in the Olfactory Bulb of the Human Brain

This case series provides evidence of MPs found in the human olfactory bulb, suggesting a potential pathway for the translocation of MPs to the brain. The findings underscore the need for further research on the health implications of MP exposure, particularly concerning neurotoxicity and the potential for MPs to bypass the blood-brain barrier.

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Discovery and analysis of microplastics in human bone marrow
Reports Andrew Craigie Reports Andrew Craigie

Discovery and analysis of microplastics in human bone marrow

Pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS) is an emerging thermal analysis technique that reliable qualified and quantified data for MPs risk assessment of human health [15], [26]. Laser direct infrared spectroscopy (LD-IR) has been widely used to characterize of MPs, including their type, size, and morphology [12]. This study utilized Py-GC/MS, LD-IR, and scanning electron microscopy (SEM) to analyze and identify the accumulation of MPs in the bone marrow. The results provide crucial data for evaluating the risks of MPs on human haematopoietic injury, and support further studies with larger sample sizes and more detailed designs to explore the health implications of MPs in human bone marrow.

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Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis
Reports Andrew Craigie Reports Andrew Craigie

Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis

Our study revealed the presence of microplastics in all canine and human testes, with significant inter-individual variability. Mean total microplastic levels were 122.63 µg/g in dogs and 328.44 µg/g in humans. Both humans and canines exhibit relatively similar proportions of the major polymer types, with PE being dominant. Furthermore, a negative correlation between specific polymers such as PVC and PET and the normalized weight of the testis was observed. These findings highlight the pervasive presence of microplastics in the male reproductive system in both canine and human testes, with potential consequences on male fertility.

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State of the Science On Plastic Chemicals
Reports Andrew Craigie Reports Andrew Craigie

State of the Science On Plastic Chemicals

Although there is a wealth of scientific information on plastic chemicals and polymers to inform policymakers, implementing this evidence is challenging because information is scattered and not easily accessible. The PlastChem report and database address this issue by comprehensively and consistently synthesizing the state of the science on plastic chemicals, including their hazard properties, and their presence in polymers. The state-of-the-science report provides the publicly available evidence to inform policy development that protects public health and the environment.

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PureCycle’s (PCT) Failure To Launch
Reports Andrew Craigie Reports Andrew Craigie

PureCycle’s (PCT) Failure To Launch

After a months long investigation, backed by interviews, regulatory filings, and visual evidence reveals that the facility has yet to start commercial scale production four months later. We have spoken with Ohio regulators that have contradicted company claims, and former employees that have exposed numerous issues. We believe PureCycle has mislead investors about the launch of its facility, or at the very least, will not come anywhere close to meeting production targets.

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Hazardous Chemicals in Recycled and Reusable Plastic Food Packaging
Reports Andrew Craigie Reports Andrew Craigie

Hazardous Chemicals in Recycled and Reusable Plastic Food Packaging

All types of water pipes, not only lead, can release chemicals into drinking water. Plastic pipes, which are constructed from potentially dozens of different chemicals, release more contaminants into drinking water than unlined metal pipes, which are built of few materials. Communities need to understand the potential health risks associated with different water pipe materials so that they do not end up with what’s known as a “regrettable substitution,” or a situation in which a selected alternative turns out to be just as bad, if not worse, as the original option.

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The Perils of PVC Plastic Pipes
Reports Andrew Craigie Reports Andrew Craigie

The Perils of PVC Plastic Pipes

All types of water pipes, not only lead, can release chemicals into drinking water. Plastic pipes, which are constructed from potentially dozens of different chemicals, release more contaminants into drinking water than unlined metal pipes, which are built of few materials. Communities need to understand the potential health risks associated with different water pipe materials so that they do not end up with what’s known as a “regrettable substitution,” or a situation in which a selected alternative turns out to be just as bad, if not worse, as the original option.

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PVC Poison Plastic
Reports Andrew Craigie Reports Andrew Craigie

PVC Poison Plastic

Every day, PVC production exposes communities around the country to vinyl chloride and other PVC chemicals, a result of the inadequate U.S. regulatory system that allows the use of the most hazardous chemicals and plastics. This investigation uncovers the largest polluters of vinyl chloride in the U.S. and maps the communities regularly exposed to this dangerous chemical and its waste products.

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The Minderoo-Monaco Commission on Plastics and Human Health
Reports Andrew Craigie Reports Andrew Craigie

The Minderoo-Monaco Commission on Plastics and Human Health

The Minderoo-Monaco Commission on Plastics and Human Health has produced an extensive analysis of the plastics’ negative impacts on: i) human health and well-being focusing on vulnerable populations, ii) on the global environment focusing on ocean health, and iii) the economy. The report includes highly valuable sustainable solutions that can be implemented by governments and industries to minimize the negative consequences of global plastic contamination This is an urgent problem that must be addressed in the worldwide agenda in parallel to climate change, as they are closely interconnected.

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Detection of Microplastics in Human Saphenous Vein Tissue Using μFtir: A Pilot Study
Reports Andrew Craigie Reports Andrew Craigie

Detection of Microplastics in Human Saphenous Vein Tissue Using μFtir: A Pilot Study

Microplastics (MPs) are ubiquitous in the environment, in the human food chain, and have been recently detected in blood and lung tissues. To undertake a pilot analysis of MP contamination in human vein tissue samples with respect to their presence (if any), levels, and characteristics of any particles identified. This study analysed digested human saphenous vein tissue samples (n = 5) using μFTIR spectroscopy (size limitation of 5 μm) to detect and characterise any MPs present.

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Microplastics Occurrence, Health Effects, and Mitigation Policies: An Evidence Review for the California State Legislature
Reports Andrew Craigie Reports Andrew Craigie

Microplastics Occurrence, Health Effects, and Mitigation Policies: An Evidence Review for the California State Legislature

This report responds to a joint request from the California Senate Committee on Environmental Quality and the Assembly Committee on Natural Resources for evidence concerning human health effects of microplastics and public policies related to microplastics prevention and mitigation.

Research was conducted by the California State Policy Evidence Consortium (CalSPEC), anindependent program administered through the University of California Center Sacramento (UCCS) and composed of faculty, staff, and graduate student researchers across UC campuses who evaluate evidence to inform public policy deliberations.

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