We show that circulating MPs are phagocytosed and lead these cells to obstruction in the capillaries of the brain cortex. These blockages as thrombus formation cause reduced blood flow and neurological abnormalities in mice. Our data reveal a mechanism by which MPs disrupt tissue function indirectly through regulation of cell obstruction and interference with local blood circulation, rather than direct tissue penetration.

We concluded that exposure to microplastics is “unclassifiable” for birth outcomes and gestational age in humans on the basis of the “low” and “very low” quality of the evidence. We concluded that microplastics are “suspected” to harm human reproductive, digestive, and respiratory health, with a suggested link to colon and lung cancer. Future research on microplastics should investigate additional health outcomes impacted by microplastic exposure and identify strategies to reduce exposure.

The study shows plastic exposure as a significant CVD risk factor regardless of duration. It leads to changes in myocardial tissue, gut microbiota, and metabolites, all closely tied to CVD.

In this brief, we present highlights from the significant body of science indicating that plastic building materials are contributing to serious health and environmental harms over their life cycle, from fossil fuel extraction to production, use, and disposal. These impacts fall disproportionately on susceptible and marginalized people, including women, children, Indigenous people, low-income communities, and people of color. We share examples of solutions and offer recommendations to strengthen policies that will reduce plastic use in the built environment and associated life cycle harms.

This study presents the first definitive confirmation of microplastic presence in the human stomach, based on samples from 26 cadavers. 97 microplastic particles were extracted from stomach contents, across all 26 individuals, revealing a universal prevalence of microplastics in the cadavers.

Our findings highlight the potential reproductive health risks posed by microplastic contamination, particularly PTFE, a non-stick pan coating material, and raise concerns about the potential of urine testing as an indicator of male reproductive microplastic exposure. Future research is warranted to further elucidate the mechanisms underlying the adverse effects of microplastics on male fertility and cross-generational effects.

This case series provides evidence of MPs found in the human olfactory bulb, suggesting a potential pathway for the translocation of MPs to the brain. The findings underscore the need for further research on the health implications of MP exposure, particularly concerning neurotoxicity and the potential for MPs to bypass the blood-brain barrier.

Pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS) is an emerging thermal analysis technique that reliable qualified and quantified data for MPs risk assessment of human health [15], [26]. Laser direct infrared spectroscopy (LD-IR) has been widely used to characterize of MPs, including their type, size, and morphology [12]. This study utilized Py-GC/MS, LD-IR, and scanning electron microscopy (SEM) to analyze and identify the accumulation of MPs in the bone marrow. The results provide crucial data for evaluating the risks of MPs on human haematopoietic injury, and support further studies with larger sample sizes and more detailed designs to explore the health implications of MPs in human bone marrow.

Ohio River Valley Institute’s July 2024 report explores the many reasons why chemical recycling is a false promise for the region, from hazardous chemicals, to greenhouse gas emissions, the habitat and ecosystem degradation, to the technology’s expense and general lack of success, and more.

Our study revealed the presence of microplastics in all canine and human testes, with significant inter-individual variability. Mean total microplastic levels were 122.63 µg/g in dogs and 328.44 µg/g in humans. Both humans and canines exhibit relatively similar proportions of the major polymer types, with PE being dominant. Furthermore, a negative correlation between specific polymers such as PVC and PET and the normalized weight of the testis was observed. These findings highlight the pervasive presence of microplastics in the male reproductive system in both canine and human testes, with potential consequences on male fertility.

Rising global concentrations of environmental micro- and nanoplastics (MNPs) drive concerns for human exposure and health outcomes. Applying pyrolysis gas chromatography-mass spectrometry (Py-GC/MS) methods to isolate and quantify MNPs from human samples, we compared MNP accumulation in kidneys, livers, and brains.

Although there is a wealth of scientific information on plastic chemicals and polymers to inform policymakers, implementing this evidence is challenging because information is scattered and not easily accessible. The PlastChem report and database address this issue by comprehensively and consistently synthesizing the state of the science on plastic chemicals, including their hazard properties, and their presence in polymers. The state-of-the-science report provides the publicly available evidence to inform policy development that protects public health and the environment.

Plastic waste is a growing problem, and as plastics break down the pieces can be problematic. A new study in Science Advances suggests that tiny plastic particles may be the latest environmental contributor to Parkinson’s disease (PD)

Plastic waste is a growing problem, and as plastics break down the pieces can be problematic. A new study in Science Advances suggests that tiny plastic particles may be the latest environmental contributor to Parkinson’s disease (PD)

Our findings demonstrate the presence of MPs in human joints and suggest that further studies are needed to explore the intricate associations between MPs and anatomical location, clinical diagnosis, and local cellular responses.

After a months long investigation, backed by interviews, regulatory filings, and visual evidence reveals that the facility has yet to start commercial scale production four months later. We have spoken with Ohio regulators that have contradicted company claims, and former employees that have exposed numerous issues. We believe PureCycle has mislead investors about the launch of its facility, or at the very least, will not come anywhere close to meeting production targets.

All types of water pipes, not only lead, can release chemicals into drinking water. Plastic pipes, which are constructed from potentially dozens of different chemicals, release more contaminants into drinking water than unlined metal pipes, which are built of few materials. Communities need to understand the potential health risks associated with different water pipe materials so that they do not end up with what’s known as a “regrettable substitution,” or a situation in which a selected alternative turns out to be just as bad, if not worse, as the original option.

All types of water pipes, not only lead, can release chemicals into drinking water. Plastic pipes, which are constructed from potentially dozens of different chemicals, release more contaminants into drinking water than unlined metal pipes, which are built of few materials. Communities need to understand the potential health risks associated with different water pipe materials so that they do not end up with what’s known as a “regrettable substitution,” or a situation in which a selected alternative turns out to be just as bad, if not worse, as the original option.